Mastectomy is the surgical removal of all or part of a breast, sometimes including excision of the underlying pectoral muscles and regional lymph nodes, usually performed as a treatment for cancer. Double Mastectomy means doing it on both breasts. BRCA1 and BRCA2 are human genes that belong to a class of genes known as tumor suppressors and when they are not good, they can enhance the possibility of breast cancer leading to mastectomy.
BRCA1 and BRCA2 are acronyms that stem from the full names of the genes: BReast CAncer susceptibility gene 1 and BReast CAncer susceptibility gene 2.
BRCA1 is a human gene that helps in ensuring the stability of the DNA and helps prevent uncontrolled cell growth which becomes tumors or breast cancer.
BRCA2 like BRCA1 is a human gene that helps in ensuring the stability of the DNA and helps prevent uncontrolled cell growth which becomes tumors or breast cancer.
According to the US Government Cancer site, the probability that breast or ovarian cancer is associated with a harmful mutation in BRCA1 or BRCA2 is high in families that have a history of multiple cases of breast cancer. This is what ultimately leads to mastectomy.
Blood tests at a hospital can help detect BRCA1 and BRCA2 mutations, according to the National Cancer Institute. Results could tell whether one needs to undertake a mastectomy.